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Lexapro VS. Zoloft – Check Which Is Good For You

Lexapro VS. Zoloft

Lexapro vs. Zoloft Both Zoloft and Lexapro can be used to treat depression and other mental health issues. In addition, doctors prescribe Zoloft for various mental health issues, such as panic disorder, and Lexapro for generalized anxiety disorder.

It can be challenging to distinguish between the many depression and anxiety drugs that are available on the market. Two of the more popular drugs for mood disorders, including depression, include Lexapro and Zoloft.

These drugs are selective serotonin reuptake inhibitors (SSRIs), a kind of antidepressant. Serotonin, a chemical in the brain that aids in mood maintenance, is increased by SSRIs.

Continue reading to find out more about the similarities and differences between Zoloft (sertraline) and Lexapro (escitalopram).

Features of Lexapro and Zoloft

Generalized anxiety disorder and depression are both treated with Lexapro. Obsessive-compulsive disorder, depression, and a number of other mental health issues are all treated with Zoloft.

The conditions each medicine is authorized to treat are contrasted in the table below.

ConditionsLexaproZoloft
DepressionDo not takeDo not take
Generalized Anxiety DisorderDo not take
OCDDo not take
Panic DisorderDo not take
PTSDDo not take
Social Anxiety DisorderDo not take
PMDDDo not take

Lexapro Pros

  • First-choice medicine for depression and anxiety.
  • As opposed to sertraline (Zoloft), it has fewer medication interactions.
  • Possesses fewer negative effects than paroxetine (Paxil)
  • Children as young as 12 years old can use it (just for depression).
  • It can be consumed either with or without food.

Lexapro Cons

  • Up to two months pass before you begin to experience the full effects.
  • Risk of sexual issues.
  • It can make you more likely to bleed.
  • Risk of experiencing withdrawal symptoms if you stop taking it quickly.

Zoloft Pros

  • A first-choice treatment for depression and anxiety.
  • One of the SSRIs that is most secure to use when nursing or pregnant.
  • Accessible as a less expensive generic.
  • Typically one oral dose each day.

Zoloft Cons

  • It can result in withdrawal symptoms if you stop taking it suddenly.
  • It may make it more challenging for you to get to sleep.
  • In liquid form, alcohol is present.

Lexapro Side Effects in Women

Medication effectiveness, particularly with SSRIs, varies. Because of the typical differences between men’s and women’s symptoms and causes of depression and anxiety, women may react to SSRIs better than men.

Studies suggest that, despite being inconclusive, women respond better to SSRIs than males do due to their somewhat different body chemistry. In general, women tend to accumulate more Lexapro and do so more slowly than men. Although limited data suggests women are more likely than men to experience these side effects, men and women typically have similar side effects from taking Lexapro.

The studies have not been conclusive, and the side effect variations are thought to be clinically small. Thus, the current recommendations do not advise beginning women on lower doses of Lexapro. If someone is having adverse effects or trouble taking Lexapro, it is advised to reduce dosages as needed on a patient-specific basis based on patterns in the data that are currently available.

Common Side Effects of Lexapro and Zoloft

LexaproZoloft
HeadacheDiarrhea
NauseaNausea
Ejaculation ProblemDry Mouth
Dry MouthTrouble Sleeping
SleepinessSleepiness
Diarrhea
Trouble Sleeping
Fatigue

Warning

Conditions of Concern

Many of the same cautions for use with other medical conditions are present in both Lexapro and Zoloft.

For instance, if you are pregnant or want to get pregnant, you should consult your doctor.

Both of these medications have been shown to have negative effects on the fetus in studies on animals. There isn’t enough human research on Lexapro or Zoloft to know for sure how they could impact the developing baby. Only use these medications if the possible benefits outweigh the possible risks.

Risk of Death

The risk of suicide ideation and action in children, adolescents, and young adults is increased by both Lexapro and Zoloft. In actuality, the Food and Drug Administration (FDA) has only authorized Zoloft for OCD therapy in children younger than the age of 18. It is not recommended that children under the age of 12 use Lexapro.

Possible Withdrawal

It is not advisable to abruptly discontinue taking an SSRI like Lexapro or Zoloft. Unexpectedly stopping these drugs might result in withdrawal symptoms, which can include:

  • Flu-like signs
  • Agitation
  • Dizziness confusion
  • Headaches, anxiousness, and difficulty sleeping

Speak to your doctor if you need to discontinue taking one of these drugs. Your dose will be gradually reduced to aid with withdrawal symptoms.

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